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A Study Comparing Interferential Therapy and TENS Combined with Exercise for Chemotherapy-Induced Peripheral Neuropathy in Oral Cancer Survivors

Comparative Efficacy of Interferential Therapy vs TENS Combined with Neuromuscular Training on Neuropathic Symptoms, Psychological Status and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy among Oral Cancer Survivors: A Comparative Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112445
Enrollment
42
Registered
2026-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G620- Drug-induced polyneuropathy

Interventions

Intervention1: Interferential Therapy Combined with Neuromuscular Training: Participants will receive Interferential Therapy applied to the affected upper and lower limbs using standard clinical param

Sponsors

Datta Meghe Institute of Higher Education and Research DU Sawangi Meghe
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Patients receiving chemotherapy. - Patients with neuropathic symptoms associated with CIPN such as tingling, numbness, or burning in hands or feet. - Patients who provide written informed consent to participate.

Exclusion criteria

Exclusion criteria: - Patients with pre-existing neurological disorders (e.g., diabetic neuropathy, stroke, multiple sclerosis). - Patients with pacemakers, metallic implants, or seizure history. - Patients with severe cardiac, renal, or hepatic diseases affecting participation. - Patients with severe cognitive impairment or psychiatric illness preventing reliable assessment. - Patients which not able to understand and follow instructions for interventions and assessments.

Design outcomes

Primary

MeasureTime frame
NCI Common Terminology Criteria for Adverse Events (CTCAE)Timepoint: Baseline, 8th week—

Secondary

MeasureTime frame
PainDETECT QuestionnaireTimepoint: Baseline, 8th week;European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (EORTC QLQ-CIPN20)Timepoint: Baseline, 8th week;Hospital Anxiety and Depression Scale (HADS)Timepoint: Baseline, 8th week—

Countries

India

Contacts

Public ContactBhumika Langade

Ravi Nair Physiotherapy College, Datta Meghe Institute of Higher Education and Research (DU)

vaishnavi.yadav@dmiher.edu.in9595751274

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026