FindTrial
Sign In

Determining the Optimal Heparin Dose During Cardiac Surgery in Obese Patients Using a Heparin Dose Response Curve: A Prospective Randomized Controlled Study

Heparin Dose Response Curve for Heparin Dose Determination During Cardiopulmonary Bypass for Cardiac Surgery in Obese Patients : A Prospective Randomised Controlled Trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112243
Enrollment
130
Registered
2026-06-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Heparin will be administered by dose response curve. So this is our test group.: Cardiac surgical patients are routinely administered 4 milligram per kilogram of heparin. We are trying

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cardiac Surgical Patients with Basal Metabolic index more than 30

Exclusion criteria

Exclusion criteria: Patients not giving consent, patients already on heparin, emergency surgery, redo surgery

Design outcomes

Primary

MeasureTime frame
The primary outcome of the study will be the total heparin dose required to achieve target ACT (480 seconds) before initiation of CPB.Timepoint: 3 minutes after administering heparin, 72 hours after shifting to ICU—

Secondary

MeasureTime frame
,To compare total dose of heparin given in both the groups, To compare protamine dose administered in both the groups,To compare amount of postoperative blood loss between the study groups. Timepoint: 72 hours after surgery—

Countries

India

Contacts

Public ContactNeeti Makhija

All India Institute of Medical Sciences, New Delhi

neetimakhija21@gmail.com9810452292

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026