None listed
Conditions
Interventions
Intervention1: Administration of Intravenous Magnesium Sulphate: Group A -will be administered with 40mg/kg Inj. magnesium sulphate in 100 ml NS, infused in 10 minutes before induction of anesthesia.
Sponsors
Shri Ram Murthi Smarak Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: ASA Physical Status I / II Patients udergoing elective surgery under General Anesthesia
Exclusion criteria
Exclusion criteria: Patient refusal ASA grade III / IV Pregnancy Emergency Cases Contraindication for succinylcholine History of Neuromuscular disease Patients taking Calcium Channel blockers, Beta Blockers Systemic Diseases Substance Abuse Hyperkalemia Allergy to study drugs Patients requiring post operative ICU and Ventilation Long duration of surgery(more than 2 hours)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effects of prophylactic intravenous magnesium sulphate versus vitamin C on succinylcholine- induced fasciculations and postoperative myalgia in patients undergoing elective surgery under general anesthesiaTimepoint: 1.Baseline 2.After study drugs 3.After induction 4.After intubation 15 min 30 min 45min 60 min 75min 90 min 105 min 120 min | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the effect of intravenous Magnesium Sulphate on succinylcholine- induced fasciculations & postoperative myalgia in patients undergoing elective surgery under general anesthesia.Timepoint: 1.Baseline 2.After study drugs 3.After induction 4.After intubation 15 min 30 min 45min 60 min 75min 90 min 105 min 120 min;To evaluate the efficacy of intravenous Vitamin C on succinylcholine- induced fasciculations & postoperative myalgia in patients undergoing elective surgery under general anesthesia.Timepoint: 1.Baseline 2.After study drugs 3.After induction 4.After intubation 15 min 30 min 45min 60 min 75min 90 min 105 min 120 min;To compare the effect of intravenous Magnesium Sulphate & Vitamin C in succinylcholine - induced fasciculations & postoperative myalgia.Timepoint: 1.Baseline 2.After study drugs 3.After induction 4.After intubation 15 min 30 min 45min 60 min 75min 90 min 105 min 120 min;To observe the adverse effect associated with the study drugsTimepoint: 1.Baseline 2.After study drugs 3.After induction 4.After intubation 15 min 30 min 45min 60 min 75min 90 min 105 min 120 min | — |
Countries
India
Contacts
Public ContactDr Ashita Mowar
Shri Ram Murthi Smarak Institute of Medical Sciences
Outcome results
None listed