Health Condition 1: K808- Other cholelithiasis
Conditions
Interventions
Intervention1: Planosetron: Patients randomized to the intervention group will receive Palonosetron 0.075 mg IV, administered prior to induction of anesthesia for prevention of post operative nausea a
Sponsors
Shri Guru Ram Rai Institute of Medical and Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged between 18 to 60 years of either gender. 2.ASA Classification: ASA physical status I and II.
Exclusion criteria
Exclusion criteria: 1.Patients with history of severe drug reaction or known hypersensitivity to any of study medications. 2.Chronic opioid use or history of substance abuse. 3.Use of Other Antiemetics: Patients already receiving antiemetic therapy that might interfere with the studys outcomes e.g., corticosteroids or other antiemetic drugs, 24hrs prior to surgery. 4.Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting (PONV)Timepoint: Assessed at 0 2 hours, 2 6 hours, 6 12 hours, and 12 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To evaluate the duration of effectiveness of both drugs in preventing PONV. 2.To assess the incidence of any side effects of both antiemetic drugs. 3.To determine the need of rescue medication for post operative nausea and vomiting in each treatment group.Timepoint: 0 to 6 hours, 6 to 12 hours, 12 to 24 hours | — |
Countries
India
Contacts
Public ContactLavleen Khurana
Shri Mahant Inderesh Hospital, Dehradun
Outcome results
None listed