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Comparative Efficacy of Erector Spinae Plane Block Versus Intercostal Nerve Block for Postoperative Analgesia Following Gender-Affirming Breast Augmentation Surgery in Transgender Women

Efficacy of erector spinae block vs. intercostal nerve block for postoperative analgesia following breast augmentation surgery among transgender females - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112154
Enrollment
50
Registered
2026-06-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F640- Transsexualism

Interventions

Intervention1: Ultrasound-guided bilateral Erector Spinae Plane Block (ESB) : Participants will be randomized into two groups after induction of standardized general anesthesia. The ESB group will rec

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Transgender males post-orchidectomy on estrogen therapy 2. Age 18-60 years 3. ASA PS I-III

Exclusion criteria

Exclusion criteria: 1. Those with significant liver or renal dysfunction 2. COPD, bronchial asthma 3. Allergy to ropivacaine 4. Local infection 5. On antidepressants or anxiolytics

Design outcomes

Primary

MeasureTime frame
Duration of postoperative analgesiaTimepoint: post operative day 1(first 24 hours)

Secondary

MeasureTime frame
Secondary outcomes include postoperative VAS pain scores, intraoperative fentanyl requirement, total postoperative rescue analgesic consumption, intraoperative sevoflurane consumption, and incidence of adverse events such as postoperative nausea and vomiting (PONV), pneumothorax, and local anesthetic systemic toxicity.Timepoint: Postoperative pain scores will be assessed using the Visual Analogue Scale (VAS) at 0, 2, 4, 6, 12, and 24 hours after surgery. Intraoperative variables including fentanyl and sevoflurane consumption will be recorded during surgery. Rescue analgesic requirement and adverse events will be monitored during the first 24 postoperative hours, and patients will be followed up on postoperative day one.

Countries

India

Contacts

Public Contactaishwarya prasad

Amrita institute of medical sciences

aishwaryaprasad1906@gmail.com9447464652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026