Health Condition 1: F32- Major depressive disorder, singleepisode Health Condition 2: F33- Major depressive disorder, recurrent
Conditions
Interventions
Intervention1: Yoga-philosophy based psychotherapy (Pratipakshabhavana): Duration: 2 weeks of intervention with follow-up for 11 months. The study will be conducted in two phases. In Phase 1, a pilot
Sponsors
Central Council for Research in Yoga and NAturopathy
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adults aged 18 to 60 years of all genders 2.Major Depressive Disorder (single episode or recurrent, without psychotic features), confirmed by DSM-5 criteria using DIAMOND interview and with HAM-D score of 14 or more. 3.Currently receiving antidepressant medication with stable dosage for at last 8 weeks, or medication-naive 4.Ability to provide written informed consent in Kannada or English or Hindi.
Exclusion criteria
Exclusion criteria: 1.Suicidal ideation with intent within the past one month, as assessed by the Columbia Suicide Severity Rating Scale (C-SSRS) 2.Current or past diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, substance use disorder (except tobacco), or obsessive-compulsive disorder, as identified by clinical evaluation or DIAMOND screening 3. Persistent Depressive Disorder (dysthymia) as the primary diagnosis 3.Cognitive impairment precluding participation in group sessions 4.Individuals currently undergoing ECT and/or any kind of structured psycho-therapy interventions for depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale Timepoint: Initial pilot feasibility study (n = 10) time points: Baseline 2 weeks 6 weeks and 12 weeks Main RCT study time points: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Rosenberg Self Esteem ScaleTimepoint: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year;WHO 5 Well Being IndexTimepoint: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year ;Satisfaction with Life ScaleTimepoint: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year ;Difficulties in Emotion Regulation ScaleTimepoint: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year ;Beck Depression InventoryTimepoint: Baseline 2 weeks 6 weeks 12 weeks 24 weeks 1 year ;Yogic Assessment of Mental Afflictions (YAMA)Timepoint: Baseline 6 weeks 12 weeks 24 weeks 1 year;Path of Yoga ScaleTimepoint: Baseline 6 weeks 12 weeks 24 weeks 1 year | — |
Countries
India
Contacts
Public ContactDr Hemant Bhargav
NIMHANS
Outcome results
None listed