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Study of signs of inflammation in saliva and gum fluid in patients with gum disease

Association of Salivary and Gingival Crevicular Fluid Inflammatory Biomarkers (IL1 beta, TNF alpha and CRP) with Clinical Severity of Periodontitis: A Clinical Observational Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/06/112088
Enrollment
80
Registered
2026-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Swami Vivekanand Subharti University Meerut Uttar Pradesh Indi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy individuals Patients diagnosed with periodontitis based on clinical parameters Individuals willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Systemic diseases affecting periodontal status Pregnancy or lactation Antibiotic therapy within the previous 3 months Recent periodontal therapy Tobacco users.

Design outcomes

Primary

MeasureTime frame
Levels of IL1beta TNF alpha and CRP in saliva and gingival crevicular fluid among periodontitis patients and periodontally healthy individualsTimepoint: At baseline—

Secondary

MeasureTime frame
Correlation of IL1 beta TNF alpha and CRP levels with Plaque Index Gingival Index Probing Pocket Depth and Clinical Attachment LevelTimepoint: At baseline following clinical periodontal examination;Comparison of biomarker levels between periodontitis patients and periodontally healthy individualsTimepoint: At baseline—

Countries

India

Contacts

Public ContactShivi Khattri

Subharti Dental College and Hospital Swami Vivekanand Subharti University

shivikhattri123@gmail.com9627600088

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026