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How two different ventilator settings affect airway pressures during gallbladder removal done with keyhole surgery.

Comparative evaluation of airway pressure changes in volume control versus pressure control mode in laparoscopic cholecystectomy. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112030
Enrollment
100
Registered
2026-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Group VC: The ventillator parameters will be set such that tidal volume 6-8 ml per kg, respiratory rate 12 per minute, inspiration to expiratory ratio is 1:2 and maximum alarm setting o

Sponsors

Government Medical College, Amritsar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of Age 18-70 years, any gender. 2. American society of Anaesthesiologists (ASA) grade I-II. 3. Elective laparoscopic cholecystectomy surgery under General anaesthesia. 4. Duration of surgery less than 2 hours. 5. Patients who are willing to provide written, fully informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with Mallampatti grading III and IV or Difficult airway. 2. Male or female less than 18 yrs of age or more than 70 years of age. 3. Patients who have had laparoscopic procedures before. 4. Patients who experience allergic responses to anaesthetics. 5. Surgical duration beyond 2 hours. 6. Known history of Chronic obstructive pulmonary disease (COPD). 7. Patients who will have intraoperative hemodynamic instability. 8. Patients who will require conversion to open cholecystectomy procedure intraoperatively. 9. Patients with BMI more than 35. 10. Intra operative usage of an airway device other than tracheal tube. 11. Requirement for mechanical ventilation in post op period.

Design outcomes

Primary

MeasureTime frame
The primary goal is to assess the effectiveness of ventilation by examining Peak airway pressure (Ppeak/PIP) Mean airway pressure (Pmean) Expiratory tidal volume Plateau airway pressure (P plateau) ETCO2.Timepoint: Respiratory parameters will be recorded at 10 minutes after induction of anaesthesia, After pneumoperitoneum( parameters will be measured every 5 minutes interval till the end of surgery), and after desufflation.

Secondary

MeasureTime frame
To compare the efficacy of hemodynamic response by evaluating variables such as heart rate,oxygen saturation, systolic blood pressure, diastolic blood pressure and mean arterial pressure, in volume control vs pressure control ventilation.Timepoint: These parameters will be recorded at 10 minutes after induction of anaesthesia, After pneumoperitoneum( parameters will be measured every 5 minutes interval till the end of surgery), and after desufflation.

Countries

India

Contacts

Public ContactDr Rajan Kumar

Government Medical College

rajan.verma0102@gmail.com9815267049

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026