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Assessment of brain pressure changes during endotracheal suctioning in ventilated patients

Dynamic changes in optic nerve sheath diameter during endotracheal suctioning - A prospective observational study on intracranial recovery time - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111998
Enrollment
50
Registered
2026-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R908- Other abnormal findings on diagnostic imaging of central nervous system

Interventions

Intervention1: Endotracheal suctioning: Mechanically ventilated adult ICU patients requiring routine endotracheal suctioning will undergo suctioning as per institutional ICU protocol. Optic nerve shea

Sponsors

PES Institute of Medical Sciences and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult mechanically ventilated patients with endotracheal tube. Hemodynamically stable patients requiring routine endotracheal suctioning. Consent obtained from patient attendant.

Exclusion criteria

Exclusion criteria: Known optic nerve pathology. Ocular trauma or orbital edema. Raised intraocular pressure. Severe hemodynamic instability. Contraindications to ultrasound examination.

Design outcomes

Primary

MeasureTime frame
Dynamic changes in optic nerve sheath diameter during and after endotracheal suctioningTimepoint: Dynamic changes in optic nerve sheath diameter during and after endotracheal suctioning

Secondary

MeasureTime frame
Intracranial recovery time defined as time taken for optic nerve sheath diameter to return to baselineTimepoint: Immediately after suctioning, 1 minute, 3 minutes, 5 minutes and 10 minutes post suctioning;Correlation of optic nerve sheath diameter changes with heart rate, blood pressure and oxygen saturationTimepoint: Baseline, during suctioning, immediately after suctioning, 1 minute, 3 minutes, 5 minutes and 10 minutes post suctioning

Countries

India

Contacts

Public ContactDr Alekhya Sai Guntupalli

PES Institute of Medical Sciences and Research

g.alekhyasai@outlook.com9030476936

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026