A Study of Recovery After Surgery in Children Receiving Propofol With or Without Remifentanil

Effect of Remifentanil addition to Propofol Target Controlled Infusions (Paedfusor model) on recovery profile in paediatric surgical patients: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/111966

Enrollment

Registered

2026-06-04

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K629- Disease of anus and rectum, unspecified Health Condition 2: K36- Other appendicitis

Interventions

Intervention1: Use of Remifentanil with propofol target controlled infusion intraoperatively for induction and maintainence of anaesthesia.: The study group will receive a maintenance Remifentanil inf

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1,2. Weight more than 10 kilograms.

Exclusion criteria

Exclusion criteria: Patients who refuse to participate in the study. Patients with developmental delay, neurological injury, psychiatric diagnosis, or cardiac diseases. Patients with abnormal lipid or carbohydrate metabolism. Patients with anxiety in the preoperative period who require sedative premedication. Patients with known allergy to any drug used in the study

Design outcomes

Secondary

Measure	Time frame
To compare the hemodynamic changes during the intraoperative period between the two groups.Timepoint: All parameters will be recorded every 15 minutes;To compare the incidence of emergence agitation using the PAED scale.Timepoint: After extubation in both groups;To compare postoperative pain using the VAS scale and total analgesic requirement in 24 hours. Timepoint: at 1 hour, 6 hours, 12 hours, and 24 hours, ;To compare the incidence of adverse events in the perioperative period. Timepoint: during or after surgery	—

Measure

Time frame

To compare the hemodynamic changes during the intraoperative period between the two groups.Timepoint: All parameters will be recorded every 15 minutes;To compare the incidence of emergence agitation using the PAED scale.Timepoint: After extubation in both groups;To compare postoperative pain using the VAS scale and total analgesic requirement in 24 hours. Timepoint: at 1 hour, 6 hours, 12 hours, and 24 hours, ;To compare the incidence of adverse events in the perioperative period. Timepoint: during or after surgery

—

Primary

Measure	Time frame
To compare the time to extubation in two groups.Timepoint: 0 min- just after removal of the endotracheal tube	—

Countries

India

Contacts

Public ContactDr Farah Nasreen

Jawaharlal Nehru Medical College

kazmifarah@gmail.com9897067670

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026