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This study will compare three different medicines placed inside the root canals of infected primary (baby) molars to determine which one is most effective in reducing bacterial infection before completing the root canal treatment.

A comparative evaluation of antimicrobial efficacy of three different intracanal medicaments in primary molars- an in vivo study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111940
Enrollment
45
Registered
2026-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Group 2- 3.8% Silver diamine fluoride: Commercially available 38% Silver diamine fluoride will be diluted to 3.8% Silver diamine fluoride freshly prepared and will be placed as medicine

Sponsors

Dr Nilisha Aggarwal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy children (ASA I score), both male and female, aged between 4 to 7 years, with a behaviour rating of 3 or 4 according to the Frankl scale. Mandibular primary molars with necrotic/ non vital pulp, having at least two thirds of root length with no evidence of pathological root resorption. Teeth with restorable crowns.

Exclusion criteria

Exclusion criteria: Children with systemic illness or special healthcare needs. Presence of any abscess, sinus or fistula. Teeth with developmental defects or pathological mobility. Patients who have the history of antibiotic course for at least 1 week before the study. Children with a known history of allergy or hypersensitivity to any of the study medicaments or their components (silver, fluoride, antibiotics, or herbal preparations).

Design outcomes

Primary

MeasureTime frame
To compare the antimicrobial efficacy of Three Intracanal medicaments in primary teeth root canals.Timepoint: Outcome will be assessed at baseline, and after 1 week.

Secondary

MeasureTime frame
To evaluate the antimicrobial efficacy of each intracanal medicament in primary teeth root canals independently.Timepoint: At baseline, & after 1 week.

Countries

India

Contacts

Public ContactDr Nilisha Aggarwal

RAJASTHAN UNIVERSITY OF HEALTH SCIENCES

dr.ambika.rathore@gmail.com8107132663

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026