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Effect of using low flow and very low flow of gases for providing anaesthesia in patients undergoing elective surgical procedures.

Comparative efficacy of low flow versus minimal flow anaesthesia in reducing the desflurane consumption and patient outcomes in laparoscopic cholecystectomy: a randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111917
Enrollment
60
Registered
2026-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Minimal flow group: A flow of 500 ml per minute will be used during maintenance of anaesthesia Control Intervention1: Low flow group: Flow rate of 1 litre per minute will be used during

Sponsors

All India Institute of Medical Sciences, Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 18 to 65 years of age of either sex ASA I or ASA II undergoing laparoscopic cholecystectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patients with uncontrolled hypertension patients with chronic lung pathologies patients with cardiac comorbidities

Design outcomes

Primary

MeasureTime frame
To compare the desflurane consumption in both the groupsTimepoint: At the end of surgery

Secondary

MeasureTime frame
To compare the mean recovery time (RASS of -1 or 0) in both the groupsTimepoint: At the end of surgery;To compare the intraoperative EtCO2 after pneumoperitoneum, at 15 mins, 30 mins, 45 mins and at extubation, in both the groupsTimepoint: During creation of pneumoperitoneum, 15 mins, 45 mins, at extubation;To compare the relative incidence of adverse effects in both the groupsTimepoint: Any time during or at the end of surgery

Countries

India

Contacts

Public ContactDr Anirban Brahma Adhikary

All India Institute of Medical Sciences, Rishikesh

anirbanadhikary84@gmail.com8486241661

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026