A study comparing clonidine and dexmedetomidine added to local anaesthetics for ultrasound-guided interscalene nerve block in shoulder and upper arm surgeries.

A Comparative Study of Levobupivacaine with Clonidine versus Levobupivacaine with Dexmedetomidine in Ultrasound Guided Interscalene Block for Elective shoulder and proximal humerus surgeries A Randomised Controlled Trial. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/111863

Enrollment

Registered

2026-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: inj levobupivacaine with inj clonidine: inj.levobupivacaine 0.5% 15ml with inj.clonidine50mcg with 15ml Normal saline injected as a single dose in interscalene brachial plexus block Co

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patient willing to participate with written informed consent. 2)Patients belonging to ASA grade 1 and 2 of either sex. 3)Patient with age group between 18 to 60years weighing between 50 to 70 kgs.

Exclusion criteria

Exclusion criteria: 1)Known allergies to any of study drugs 2)Coagulopathies or anticoagulant therapy 3)Humerus Surgeries planned to be done in lateral position. 4)Duration of surgery exceeding more than 2hours. 5)Any infection at local site 6)Persons with COPD/any other respiratory diseases 7)Pregnancy and Lactation 8)Patients with known Cardiac disorders/Respiratory illnesses/Endocrine disorders 9)Patients who are suspected to have Neuromuscular disorders

Design outcomes

Primary

Measure	Time frame
To compare the effect of levobupivacaine with clonidine and levobupivacaine with dexmedetomidine in terms of onset and duration of sensory and motor blockade in USG guided interscalene block.Timepoint: immediately after the block and upto 24hrs	—

Secondary

Measure	Time frame
To evaluate the hemodynamic paramaters during & after giving the blockTimepoint: immediately after the block & upto 24hrs;To observe & compare any adverse effects or complications with either of the adjuvantTimepoint: upto 24hrs;To assess patient satisfaction regarding postoperative analgesia & comfort.Timepoint: upto 24hours	—

Countries

India

Contacts

Public ContactDR OVIYA J

chamarajanagar institute of medical sciences

darshanms_jss@yahoo.com9741376797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026