Health Condition 1: K319- Disease of stomach and duodenum, unspecified
Conditions
Interventions
Intervention1: Inhaled Glycopyrrolate via Rotahaler: 100mcg Glycopyrrolate will be inhaled via rotahaler.
Frequency: once, 15 minutes before anaesthesia induction
Total duration: 30 minutes.
Control I
Sponsors
Dr Pallav Singh
Eligibility
Inclusion criteria
Inclusion criteria: Posted for elective surgery under general anesthesia requiring fibreoptic-guided orotracheal intubation(awake or asleep, as per routine practice) ASA Physical Status I-III Able to provide written informed consent Anticipated difficult airway where fibreoptic intubation is planned (e.g., limited mouth opening, restricted neck movement, airway pathology) OR institutional practice where FO-guided intubation is planned by the attending anesthesiologist. American Society of Anesthesiologists (ASA) Physical Status I-III Willing to participate in the study and comply with study procedures and follow-up
Exclusion criteria
Exclusion criteria: Contraindications to Glycopyrrolate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of airway secretion burden score during fibreoptic bronchoscopy and total fibreoptic procedural time between patients receiving inhalational glycopyrrolate via Rotahaler and those receiving intramuscular glycopyrrolate.Timepoint: baseline (pre-FOB), scope insertion, midpoint of FOB, scope removal/end of FOB, and 5 minutes post-FOB. | — |
Secondary
| Measure | Time frame |
|---|---|
| bronchoscopy visibility, suction events, hemodynamics, adverse events, ease of airway device placement, operator confidence, postoperative throat discomfort, postoperative dry mouth, and other anticholinergic/inhalation-related side effects.Timepoint: during FOB for visibility, suction events, hemodynamics, and intra-procedural adverse events; immediately after device placement for ease of placement; during FOB for operator confidence; and 1, 6, and 24 hours after extubation for throat discomfort, dry mouth, and other postoperative side effects | — |
Countries
India
Contacts
Public ContactPallav Singh
SGPGIMS
Outcome results
None listed