Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention1: Neurocognitive rehabilitation (NCR): Patients shall be included in the randomized controlled trial and shall be allocated to either the intervention or the waitlist control arm using a
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Clinically, histologically diagnosed with breast cancer Stage I-III Standard anthracycline and taxane-based chemotherapy regimen Ability to read and write Should be able to give written consent to participate in the study
Exclusion criteria
Exclusion criteria: History of neuropsychiatric/neurodegenerative disorder History of metastasis to brain Any CNS related lesion, trauma, stroke etc. HMSE score less than 24
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcomes include cognitive changes across chemotherapy stages, EEG and biochemical marker evaluation, comparison with healthy controls, and effectiveness of neurocognitive rehabilitation on cognitive outcomes.Timepoint: Pre-chemotherapy (Baseline),Post-chemotherapy, and Long-term chemotherapy (after six-months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include correlation between cognitive, EEG, and biochemical findings, and evaluation of the impact of rehabilitation strategies on daily functioning and quality of life.Timepoint: Pre-chemotherapy (Baseline),Post-chemotherapy, and Long-term chemotherapy (after six-months) | — |
Countries
India
Contacts
Public ContactSimran Kaur
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed