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Comparison of Ozonized Water and Normal Saline Irrigation on Healing and Recovery After Wisdom Tooth Removal Surgery

A Comparative Evaluation of Ozonized Water and Normal Saline Irrigation on Postoperative Sequelae Following Surgical Removal of Impacted Mandibular Third Molars - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111784
Enrollment
70
Registered
2026-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ozonized Water: Antibacterial, antiviral, and antifungal action Helps reduce postoperative infection May decrease pain, edema, and dry socket incidence Improves tissue oxygenation and h

Sponsors

Dr Dhruv Baldev
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients classified as ASA I (systemically healthy) Patients aged 18 35 years Patients requiring surgical removal of bilateral impacted mandibular third molars Patients willing to participate in the study and provide written informed consent

Exclusion criteria

Exclusion criteria: Patients with systemic diseases (diabetes, immunocompromised status, bleeding disorders) Pregnant or lactating females Smokers and tobacco users Patients with a history of radiation therapy or organ transplantation Patients allergic to local anaesthetic agents Patients who have taken antibiotics, anti-inflammatory or antimicrobial drugs within 7 days prior to surgery Patients with acute local infection at the surgical site

Design outcomes

Primary

MeasureTime frame
Reduced postoperative pain Reduced facial swelling Reduced trismus Better wound healing Lower incidence of dry socket and postoperative infection Improved patient comfort and recovery compared to normal saline irrigationTimepoint: 1,3,7 days

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Asutosh Das

Kalinga Institute of Dental Sciences

asutosh.das@kids.ac.in9980960336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026