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Role of Bacteria and their Interaction in Periodontally Compromised Patients Preventing Endodontic Complications.

BAC GENE Atavism and Role of Bacteriocins in Periodontally Compromised patients preventing endodontic Complications- A Multicentric Experimental Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111767
Enrollment
300
Registered
2026-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Nil: Nil Control Intervention1: Adjunctive Probiotic Synbiotic Therapy with Bacteriocin Modulation in Periodontally Compromised Patients: The intervention in this study consists of adju

Sponsors

Saraswati Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults 35-55 years more than or equals to 20 teeth, Generalized periodontitis (2018 classification, stage II-III), According To ICDAS II Score 0, At least one quadrant with vital pulp teeth, Willingness for therapy and follow-up.

Exclusion criteria

Exclusion criteria: Endodontic infections requiring immediate treatment, Recent antibiotics or probiotics, Uncontrolled diabetes, Immunosuppression, Pregnancy, Allergy to study projects.

Design outcomes

Primary

MeasureTime frame
Composite incidence of Endodontic Complications (Pulp Necrosis, Symptomatic Apical Periodontitis or RCT) in Periodontally compromised Tooth Loss, Tooth Shifting, Abscesses and Gum Recession) individuals, Alteration in Endodontic Complications after probiotic therapy, Alteration in Periodontal Complications after probiotic administration, Effect of bacteriocin released from Periodontal Disease Microbes on Endodontic disease causing Microbes.Timepoint: 0, 1, 3 AND 6 MONTHS

Secondary

MeasureTime frame
Periodontal changes and Endodontic Changes Clinically and Radiographically and Vice versa with correlation of the same at the Microbial Level.Timepoint: 0, 1, 3 AND 6 MONTHS

Countries

India

Contacts

Public ContactVIVEK BAINS

Saraswati Dental College and Hospital

docvivek1976@gmail.com9935023439

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026