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Comparative study of pain on propofol injection lignocaine pre-treatment versus lignocaine -propofol admixture in adult surgical patients

A DOUBLE BLIND RANDOMISED COMPARATIVE STUDY OF LIGNOCAINE PRE-TREATMENT VERSUS LIGNOCAINE-PROPOFOL ADMIXTURE FOR THE ATTENUATION OF PAIN ON PROPOFOL INJECTION IN ADULT SURGICAL PATIENTS - NIl

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111762
Enrollment
90
Registered
2026-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: LIGNOCAINE: INJ.LIGNOCAINE 2% 0.5mg/kg Control Intervention1: PROPOFOL : INJ.PROPOFOL 2-2.5mg/kg

Sponsors

Jss Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status I and II patients of either sex between the age of 18-60 years 2.Patients undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patient with a history of allergy to egg 2.Pregnant and lactating women 3.Patients with any open wounds/fractures at the site of injection site. 4.Patients receiving pre-emptive analgesia/ analgesic intake 12 hrs prior to the surgery

Design outcomes

Primary

MeasureTime frame
Primary objective of the study is to compare which of the two methods is superior / more effective in reducing or preventing pain associated with the injection of propofol in patients who are undergoing general anaesthesia.Timepoint: From beginning of general anaesthesia till post operative recovery period

Secondary

MeasureTime frame
Secondary objective includes assessment of the vital signs (blood pressure, heart rate, respiratory rate & o2 saturation) in all participant To assess the severity of pain at the injection site among healthy adults undergoing general anaesthesia Timepoint: From beginning of general anaesthesia till post operative recovery period

Countries

India

Contacts

Public ContactDr Vyshnavi S

Jss Academy of Higher Education and Research

vyshgiri@gmail.com9880110022

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026