Health Condition 1: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Estrogen administration during Hormone Replacement Therapy for Embryo Transfer: Vaginal / Rectal Estrogen administration
Drug: Estradiol hemihydrate
Dose: 2 mg, three times daily (TDS)
Sponsors
Oasis Fertility, Hyderabad
Eligibility
Inclusion criteria
Inclusion criteria: BMI 21 35 kg per square meter Primary infertility Normal uterine cavity assessed by 3 D ultrasound (USG)/hysteroscopy HR FET cycles
Exclusion criteria
Exclusion criteria: a) Thin endometrium b) More than 2 failed transfers c) Patient needing addition of more than one route of estrogen supplementation as observed in previous cycles d) Uterine anomalies e) Underlying disorders (cardiac/renal/hepatic/thromboembolic disorders/tuberculosis, h/o anxiety or depression etc)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thicknessTimepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Serum E2 Levels at start of progesterone administration 2. Duration of treatment required 3. Compare pregnancy outcomes i,e. implantation rate and clinical pregnancy rates 4. Patient satisfaction outcome and adverse effect 5. Cost effectiveness between 3 groups Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactKrishna Chaitanya Mantravadi
Oasis Fertility, Hyderabad
Outcome results
None listed