Skip to content

Effect of non-surgical gum treatment on harmful bacteria and hormone levels in pre- and postmenopausal women.

Comparative Evaluation of Subgingival Colony Counts of Porphyromonas Gingivalis in Pre and Post Menopausal Women and Their Association with Serum Estradiol Levels After Non-Surgical Periodontal Therapy: A Clinico-Microbiological Study - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111753
Enrollment
36
Registered
2026-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non-surgical periodontal therapy: Participants with periodontitis will undergo non-surgical periodontal therapy including scaling and root planing with oral hygiene instructions. Subgin

Sponsors

Dr Vidhi Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women aged approximately 20 45 years with regular menstrual cycles and no history of menopause. Women aged more than 55 years, with natural menopause (no menstruation for 12 months). Patients with chronic periodontitis as per 2017 AAP classification. Presence of at least 20 natural teeth. Minimum of four sites with probing pocket depth (PPD) 4 mm and 7mm

Exclusion criteria

Exclusion criteria: Presence of systemic diseases known to affect periodontal status Peri menopausal age groups 40 55 years Women on hormone replacement therapy (HRT), oral contraceptives, or any hormonal medications. Patients with hysterectomy. Patients with deleterious habits (alcohol, smoking and tobacco chewing) Pregnant or lactating women. History of periodontal therapy within the past 6 months. Use of antibiotics, anti-inflammatory, or corticosteroid drugs within 3 months. Presence of acute infections, periapical pathology, or other oral mucosal lesions. Participants unwilling or unable to return for follow-up sampling or complete the study period.

Design outcomes

Primary

MeasureTime frame
Porphyromonas gingivalis colony count reductionTimepoint: Baseline

Secondary

MeasureTime frame
Change in serum estradiol levels following NSPTTimepoint: 9 months

Countries

India

Contacts

Public ContactDr Priyanka Tandon

ITS Dental College Greater Noida

drpriyanka.dntlgn@its.edu.in9140241254

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026