Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Perineural Dexamethasone Group: Patients will receive PENG block with
18 mL of 0.5% levobupivacaine + 2 mL of dexamethasone 8 mg (perineural), along
with 2 mL of normal saline adminis
Sponsors
Government Institute of Sciences(GIMS) Greater Noida
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult Patient aged 18-65 years. 2.Patients scheduled for hip surgery hemiarthroplasty, dynamic hip screw fixation, or proximal femoral nailing. 3.American Society of Anaesthesiologists physical status grade I-III. 4.Body Mass Index less than 30 kg per meter square.
Exclusion criteria
Exclusion criteria: 1.Patients with coagulopathy or on anticoagulant therapy. 2.Infection or skin disease at the site of block needle insertion. 3.Known allergy or hypersensitivity to dexamethasone, levobupivacaine, or any study drug. 4.Patients on chronic opioid therapy (for any indication) prior to surgery. 5.Patients with uncontrolled diabetes mellitus fasting blood glucose more than 200 mg per dL or HbA1c more than 9%. 6.Pre-existing neurological deficit in the lower limb(paresis, paraplegia, or motor power less than 5 by 5 in the affected limb. 7.Patients unable to comprehend or score on the Visual Analogue Scale reliably. 8.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of analgesia in minutes from completion of PENG block to first request for rescue analgesia, defined as first Visual Analogue Scale (VAS) score more than or equal 4.Timepoint: Duration of analgesia in minutes from completion of PENG block to first request for rescue analgesia | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare pain scores using Visual Analogue Scale at baseline, 1 hour, 6 hours, 12 hours, and 24 hours postoperatively between the two groups. 2.To compare total rescue analgesic consumptiona and the time to ambulation following surgery between the two groups. 3.To compare haemodynamic parameters such as heart rate, blood pressure, SpO2 at baseline and at 1, 5, 10, 30, 60, and 120 minutes. 4.To compare inflammatory and biochemical markers Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte Ratio (PLR), and blood glucose at baseline and on postoperative day 1 POD1 between the two groups. 5.To compare the drug and procedure related adverse events, if any in both groups.Timepoint: | — |
Countries
India
Contacts
Public ContactDr Anupriya Saxena
Government Institute of Medical Sciences(GIMS)
Outcome results
None listed