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Comparative study of intravenous versus intragallbladder injection of indocyanine green in the better visualization of channel taking liver juice out of liver during laparoscopic cholecystectomy

Intravenous versus intragallbladder indocyanine green (ICG) injection to delineate extra-hepatic biliary anatomy during elective laparoscopic cholecystectomy- a randomized controlled trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111708
Enrollment
280
Registered
2026-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Intravenous indocyanine green: ICG will be administered intravenously approximately 45-60 minutes prior to surgery at a concentration of 0.01 mg/kg Control Intervention1: Intragallbladd

Sponsors

NEIGRIHMSDr Ranendra Hajong
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All consenting adult patients above 18 years of age undergoing routine elective laparoscopic cholecystectomy for symptomatic gallbladder diseases will be included in the study

Exclusion criteria

Exclusion criteria: Non-consenting patients, patients below 18 years of age, patients with previous open upper abdominal surgeries, patients with acute cholecystitis, suspected or proven gallbladder cancer patients, patients with bleeding diatheses and patients with known allergy to ICG will be excluded from the study

Design outcomes

Primary

MeasureTime frame
i.To identify cystic duct, common hepatic duct, common bile duct and accessory duct during laparoscopic cholecystectomy after injecting indocyanine green (ICG) intravenous or intragallbladder and ii.To compare the rate of identification of cystic duct, common hepatic duct, common bile duct and accessory ducts during laparoscopic cholecystectomy by intravenous against intragallbladder route of administration of ICGTimepoint: at baseline and 4 weeks—

Secondary

MeasureTime frame
To collect data on i. baseline demographic profile of patients like age, gender, comorbidities, indication for surgery, ultrasonographic findings including presence or absence of impacted stone, total & direct serum bilirubin; ii. intraoperative outcomes like blood loss, time taken to dissect Calot s triangle, usage of haemostatic agents, bile spillage, stone spillage, performing antegrade cholecystectomy, performing partial cholecystectomy; iii. postoperative outcome measures like operative time, haemorrhage, bile duct injury, bile leak, etcTimepoint: baseline & at 4 weeks—

Countries

India

Contacts

Public ContactRanendra Hajong

NEIGRIHMS

ranendra.hajong@neigrihms.gov.in08787507916

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026