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Study of Ultrasound Therapy and Vitamin C on Faster Tooth Movement During Orthodontic Treatment

TO COMPARE AND EVALUATE THE EFFECT OF LIPUS THERAPY AND VITAMIN C ON ORTHODONTIC TOOTH MOVEMENT AND GINGIVAL CREVICULAR FLUID (GCF) BIOMARKERS - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111704
Enrollment
45
Registered
2026-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M268- Other dentofacial anomalies Health Condition 2: K038- Other specified diseases of hard tissues of teeth Health Condition 3: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: Conventional Orthodontic Mechanics: Rate of en masse retraction by application of conventional orthodontic mechanics only and assess Gingival Crevicular Fluid Biomarkers IL-34 and Osteo

Sponsors

Soham Chakraborty
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring maxillary first premolar extraction. Patients with Angle s Class I or Class II malocclusion. Patients with good oral hygiene and healthy periodontium. Patients with no systemic disease or medication affecting bone metabolism

Exclusion criteria

Exclusion criteria: Patients with smoking habit, pregnant, lactating patients. Patients with parafunctional habits. Patients with class III malocclusion. Patients with previous orthodontic treatment

Design outcomes

Primary

MeasureTime frame
Rate of en masse retraction of by application of LIPUS Therapy and assess Gingival Crevicular Fluid Biomarkers IL-34 and OsteopontinTimepoint: T0: Day of retraction initiation T1: After completion of 3 weeks T2: After completion of 6 weeks

Secondary

MeasureTime frame
Rate of en masse retraction by application of Injectable Vitamin C and assess Gingival Crevicular Fluid Biomarkers IL-34 and OsteopontinTimepoint: T0: Day of retraction initiation T1: After completion of 3 weeks T2: After completion of 6 weeks

Countries

India

Contacts

Public ContactSoham Chakraborty

Inderprastha Dental College and Hospital

deepti.yadav@yahoo.com8334048008

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026