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A study to compare efficacy and safety of low dose oral minoxidil vs topical minoxidil with finasteride combination for male androgenetic alopecia

A randomised comparative open label study to assess the efficacy and safety of low dose oral minoxidil vs topical minoxidil with finasteride combination for male androgenetic alopecia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111636
Enrollment
90
Registered
2026-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L649- Androgenic alopecia, unspecified

Interventions

Intervention1: minoxidil: tab minoxidil 2.5 mg OD for 9 months Control Intervention1: minoxidil with finasteride combination: topical minoxidil(5%) with finasteride (0.1%) 1 ml twice daily

Sponsors

Dr Pooja Thakur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with patterned hairloss 2. Norwood Hamilton grade 3,4,5 3. Patients who have not taken medical treatment for AGA in any form for the last 6 months

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal blood pressure or pulse rate 2. Patients with history or current evidence of associated medical condition (thyroid disorder, uncontrolled hypertension, uncontrolled diabetes mellitus, coronary artery disease, cerebrovascular or cardiovascular disease, unstable liver disease, AIDS, pheochromocytoma, etc.) 3. Patients with history or current evidence of malignancy (within last 5 years) 4. Patients with significant lab abnormalities(AST or ALT greater than 2 folds of normal, ALP greater than 1.5 folds of normal, creatinine greater than 2mg per dl, Serum PSA lever greater than 2ng per ml) 5. Patients with alopecia other than Androgenetic alopecia 6. Patients with scalp disorders like scalp psoriasis or severe seborrheic dermatitis at the area of treatment 7. Current evidence of any serious or unstable preexisting psychiatric disorder

Design outcomes

Primary

MeasureTime frame
To compare the efficacy and safety of low dose oral minoxidil(2.5mg) and topical minoxidil(5%) fortified with finasteride (0.1%) in treatment of male androgenetic alopeciaTimepoint: At baseline, 3 months, 6 months and 9 months

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Anuj Sharma

Dr. Rajendra Prasad Goverment Medical College

drkaranindermehta@gmail.com9418457647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026