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Analgesic Efficacy of Tramadol Infused PRF compared to Standard PRF following surgical extraction of mandibular third Molars - A Randomised Controlled Trial

Analgesic Efficacy of Tramadol Infused PRF compared to Standard PRF following surgical extraction of mandibular third Molars - A Randomised Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111631
Enrollment
52
Registered
2026-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R52- Pain, unspecified

Interventions

Intervention1: Tramadol Infused PRF: inj. Tramadol 1ml will be added to blood in PRF tubes before Centrifuging the tubes for preparation of tramadol infused PRF. it will be prepared by centrifuging t

Sponsors

Dr L Kartheek Reddy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 50years. 2. Indicated for surgical removal of a single, mesioangular or vertical impacted mandibular third molar 3. Systemically healthy (ASA I). 4. Willing to provide informed consent 5. Impacted teeth 1A, 1B, 2A, 2B according to pell and gregory classification

Exclusion criteria

Exclusion criteria: 1. Known Allergy to tramadol 2. Use of analgesics or corticosteroids within 48 hours prior to surgery 3. Pregnant or lactating women 4. Smokers or alcohol abusers

Design outcomes

Primary

MeasureTime frame
Tramadol Infused PRF provides significantly better post operative pain control compared to standard PRFTimepoint: pod 0 , 1, 3, 7—

Secondary

MeasureTime frame
There is no difference in Post operative pain control between tramadol infused PRF and Standard PRFTimepoint: pod 0 , 1, 3, 7—

Countries

India

Contacts

Public ContactDr L Kartheek Reddy

Yenepoya dental College

varshaupadya@yenepoya.edu.in9740536292

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026