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CBCT-Based Evaluation of Large Mandibular Bone Marrow Defects and Their Implications for Implant Planning in Patients with a History of COVID-19 and Diabetes Mellitus A Comparative Study

CBCT-Based Evaluation of Large Mandibular Bone Marrow Defects and Their Implications for Implant Planning in Patients with a History of COVID-19 and Diabetes Mellitus A Comparative Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/06/111604
Enrollment
300
Registered
2026-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged mou18 years undergoing CBCT imaging for routine dental diagnostic purposes, including implant planning. Availability of diagnostically acceptable CBCT scans adequately covering the mandibular posterior region. Presence of asymptomatic mandibular radiolucent areas suggestive of bone marrow defects on CBCT imaging For the study groups Documented history of previous COVID-19 infection confirmed through medical records, laboratory reports, or validated self-reported history Diagnosed diabetes mellitus based on medical history or physician documentation for diabetic study group

Exclusion criteria

Exclusion criteria: History of: Jaw cysts, tumors, or fibro-osseous lesions. Osteomyelitis or medication-related osteonecrosis of the jaw. Head and neck radiotherapy. Known hematologic malignancies or metabolic bone diseases other than diabetes mellitus. Evidence of: o Cortical expansion, aggressive bone destruction, or periosteal reaction. Poor-quality CBCT scans with artefacts or incomplete mandibular coverage.

Design outcomes

Primary

MeasureTime frame
To evaluate the presence and size of mandibular bone marrow defects on CBCT images in patients with a history of COVID-19 infection and diabetes mellitusTimepoint: It is a one-time radiographic assessment

Secondary

MeasureTime frame
To assess the clinical implications of large mandibular bone marrow defects for implant planning using CBCTTimepoint: It is a one-time radiographic assessment

Countries

India

Contacts

Public ContactDr Sejal Awatramaney

Hitkarini dental college and hospital

sawatramaney7@gmail.com9075201510

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026