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Study of two medicines added to spinal anaesthesia to improve pain relief after gall bladder surgery

A COMPARITIVE STUDY OF LEVOBUPIVACAINE WITH NALBUPHINE Vs LEVOBUPIVACAINE WITH BUPRENORPHINE IN THORACIC SPINAL ANAESTHESIA FOR LAPAROSCOPIC CHOLECYSTECTOMY SURGERIES - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/111553
Enrollment
60
Registered
2026-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Nalbuphine with levobupivacaine: Patients will receive intrathecal 0.5%levobupivacaine 2ml(10mg) with nalbuphine 0.4ml as an adjuvant for thoracic spinal anaesthesia. Control Intervent

Sponsors

Rvm Instutute of medical Sciences and research centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I & II Age 18-60 years daignosised with gall bladder stones

Exclusion criteria

Exclusion criteria: ASA III and above Patients hypersensitive to the drugs Patients with spinal deformities and neurological deficits Patients contraindicated to intrathecal anaesthesia Patients with coagulopathies Patients with local site infections Pregnancy and lactation Unwilling patients

Design outcomes

Primary

MeasureTime frame
Onset time and duration of sensory block and motor block following thoracic spinal anaesthesia with nalbuphine or buprenorphine as adjuvants to levobupivacaineTimepoint: at baseline, 2 minutes , 4 minutes, 6minutes, 8minutes,10minutes, 15minutes 30minutes, 45minutes,60minutes,120minutes,180minutes

Secondary

MeasureTime frame
Duration of postoperative analgesiaTimepoint: From completion of surgery to first request for rescue analgesia;Intraoperative hemodynamic variables including heart rate & blood pressureTimepoint: at baseline, 2 minutes , 4 minutes, 6minutes, 8minutes,10minutes, 15minutes 30minutes, 45minutes,60minutes,120minutes,180minutes

Countries

India

Contacts

Public Contactdr show reddy edara

rvm institute of medical sciences and research cente

edarashowreddy1988@gmail.com8971422299

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026