Health Condition 1: K861- Other chronic pancreatitis
Conditions
Interventions
Intervention1: Endoscopic ultrasound-guided celiac plexus block: Under EUS-guidance, celiac plexus block will be performed with injection of bupivacaine and triamcinolone into the area of celiac plexu
Sponsors
Orlando Health, Inc.
Eligibility
Inclusion criteria
Inclusion criteria: Age greater than or equal to 18 years. Abdominal pain of at least 3 months duration and a VAS score greater than or equal to 3, with or without the use of narcotic analgesics. Diagnosis of Chronic Pancreatitis on EUS examination, with greater than or equal to 5 features on EUS. No other cause of abdominal pain.
Exclusion criteria
Exclusion criteria: Age less than 18 years. History of prior EUS-CPB. ERCP for management of chronic pancreatitis within the last 1 year. Use of anticoagulants that cannot be discontinued for the procedure. Clinically significant allergy to bupivacaine or triamcinolone. Unable to obtain consent for the procedure from either the patient or LAR. Intrauterine pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of adequate pain reliefTimepoint: 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Technical successTimepoint: Immediately after procedure;Pain scores measured using Visual Analog Scale.Timepoint: 3 months;Pain scores measured using the Comprehensive Pain Assessment Tool-Short Form.Timepoint: 3 months;Quality of life assessmentTimepoint: 3 months;Opioid analgesic useTimepoint: 3 months;Procedure-related adverse eventsTimepoint: 3 months;Disease-related adverse eventsTimepoint: 3 months;Hospital admissions for management of chronic pancreatitis.Timepoint: 3 months;Length of hospitalization in any patient hospitalizedTimepoint: 3 months;Rate of cross-over to EUS-CPB in patients initially assigned to the sham group.Timepoint: 3 months;Rate of need for any additional endoscopic, surgical or radiological intervention for chronic pancreatitis.Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Shubham Mehta
Medanta The Medicity
Outcome results
None listed