Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
Conditions
Interventions
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Intervention3: Intraperitoneal Nebulisation: Intvervention GROUPS
GROUP RM
4ml of 0.75% Ropivacaine plus
Sponsors
Nikhila Choalla
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologist (ASA) physical classes I and II
Exclusion criteria
Exclusion criteria: Patients with a diagnosis of acute pancreatitis, acute preoperative pain other than biliary colic, known hypomagnesemia or hypermagnesemia,chronic pain treatment, uncontrolled hypertension,cardiac and renal diseases,acute asthma ,COPD,antiepileptic therapy, alcoholic,conversion to open surgery,surgery with peritoneal drain,pregnant and lactating women and allergy to ropivacaine will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesic efficacy of intraperitoneal nebulization with: Ropivacaine (R) Ropivacaine + Magnesium Sulphate (RM) Ropivacaine + Dexmedetomidine (RD) Measured by: Postoperative pain scores (VAS at multiple time points) Requirement for rescue analgesics in the postoperative periodTimepoint: Visual Analogue score for pain and rescue analgesic requirement at 0,1,2,4,8,12,16,24hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative haemodynamics like SBP,DBP,MAP,HR,SPO2 Postoperative nausea and vomiting PONV,Sedation scores and adverse effects like hypotension and bradycardia will be noted.Timepoint: SBP,DBP,MAP,HR,SPO2 at0,5,15,30,60,90,120,150,180minutes PONY and sedation scores at 0,12,4,8,12,16,24hours | — |
Countries
India
Contacts
Public ContactNikhila Choalla
Nizam s Institute Of Medical Sciences
Outcome results
None listed