Health Condition 1: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Olanzapine 5mg andOndansetron: Oral olanzapine 5 mg will be administered 1 hour before surgery with a sip of water. All patients will receive intravenous ondansetron 4 mg 30 minutes bef
Sponsors
Kirandeep Kour
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 to 60 years undergoing laparoscopic abdominal surgery under general anaesthesia with ASA physical status grade I and II and who provide written informed consent will be included in the study.
Exclusion criteria
Exclusion criteria: Patients with age less than 18 years or more than 60 years. ASA grade III or IV. Patients with cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation, torsades de pointes or QTc greater than 450 ms. Patients with history of myocardial infarction, congestive heart failure or angina. Patients with neurological disorders including Parkinson disease or dementia. Known allergy to olanzapine. Pregnant or lactating females. Patients unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting (PONV) within 24 hours after surgery using PONV intensity scaleTimepoint: 0 to 24 hrs postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first rescue antiemeticTimepoint: 0 to 24 hrs postoperatively | — |
Countries
India
Contacts
Public ContactDr Arti Mahajan
Gmc jammu
Outcome results
None listed