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Role of Chest Imaging in identifying Tuberculosis and Sarcoidosis affecting the eyes- A study at a Tertiary Eye Hospital in South India.

Assessing utility of High-resolution computed tomography chest in diagnosis of ocular tuberculosis and ocular sarcoidosis at a Tertiary eye Hospital in South India - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/111415
Enrollment
136
Registered
2026-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H30-H36- Disorders of choroid and retina

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr. Utkarsh Datta Vernekar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Clinical suspicion of ocular tuberculosis or ocular sarcoidosis based on uveitis pattern 2.Patients undergoing HRCT chest as part of systemic evaluation

Exclusion criteria

Exclusion criteria: 1.Known diagnosis of systemic TB or sarcoidosis already on treatment 2.pregnancy

Design outcomes

Primary

MeasureTime frame
1.Concordance between HRCT chest findings and treatment response in ocular tuberculosis. 2.Patients without HRCT features of TB who still receive and respond to ATT. 3.Concordance between HRCT chest findings and treatment response in ocular sarcoidosis. 4.Patients without HRCT features of sarcoidosis but show clinical improvement with immunosuppressive therapy. Timepoint: Baseline, 2 weeks, 4 weeks and at 2 months.

Secondary

MeasureTime frame
1.Correlation of Mantoux test & IGRA with HRCT chest findings Sensitivity & specificity of these tests compared to HRCT findings. 2.Correlation of adjunct imaging (e.g., USG abdomen) with HRCT chest findings To explore if extrapulmonary imaging adds diagnostic value. 3.Correlation of ocular imaging (FFA, ICGA, OCT) with HRCT chest findings To assess whether ocular imaging patterns parallel systemic radiologic findings. 4.Correlation of HRCT slice number with diagnostic yield Timepoint: Baseline, 2 weeks ,4 weeks & at 2 months.

Countries

India

Contacts

Public ContactDr Balamurugan S

Aravind eye Hospital Pondicherry

sbalamurugan@aravind.org9360384382

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026