Health Condition 1: J069- Acute upper respiratory infection,unspecified Health Condition 2: J069- Acute upper respiratory infection,unspecified
Conditions
Interventions
Intervention1: Selenium supplemention in acute lower respiratory tract infection: Oral selenium will be supplemented to one group along with ongoing standard treatment and the other group will receive
Sponsors
Dr Sofia kanagaraj
Eligibility
Inclusion criteria
Inclusion criteria: Age group 2 to 5 years included Mechanics ventilated children are also included Clinical diagnosis of acute lower respiratory tract infection are included
Exclusion criteria
Exclusion criteria: 1. Chronic respiratory conditions: o Pre-existing chronic lung diseases (asthma, cystic fibrosis, bronchopulmonary dysplasia). 2. Immunocompromised status: o Known primary or secondary immunodeficiency (HIV, chemotherapy). 3. Congenital anomalies: o Congenital heart disease or major structural lung anomalies. 4. Supplementation: o History of selenium or multivitamin supplementation containing selenium in the last 4 weeks. 5. Allergy or intolerance: o Known allergy to selenium or any component of the supplement. 6. Other concurrent infections: o Suspected or confirmed tuberculosis, or other co-infections needing different management
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.The number of days from initiation of treatment until resolution of key symptoms (fever, cough, dyspnea) will be compared in both selenium receiving group and in standard care rec eiving group 2. To explore whether selenium Supplementation contributes to faster clinical recovery such as oxygen saturation, respiratory rate, and temperature between two groupsTimepoint: The results will be assessed after 3 days and then on regular review after one month and three month of treatment completion | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Hospital Stay To evaluate the impact of oral selenium Supplementation on hospital stay duration in children with ALRTI Need for Antibiotic Escalation or Change in Treatment To compare the need for antibiotics between children receiving selenium & standard care treatment Duration of Oxygen Requirement To assess the effect of oral selenium Supplementation in terms of oxygen requirements & clinical improvement Timepoint: The results will be assessed after three days of treatment completion And then on regular review after one & three months | — |
Countries
India
Contacts
Public ContactDr Jayakumar
Government omandurar medical college
Outcome results
None listed