A study comparing two eye drop treatments to lower eye pressure in glaucoma patients

Comparative Efficacy of Timolol/ Brinzolamide Fixed Combination vs Travoprost Monotherapy in Open - Angle Glaucoma : A tertiary care study. - COMET

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2026/05/111326

Enrollment

126

Registered

2026-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

Intervention1: TIMOLOL and BRINZOLAMIDE COMBINATION .: EFFICACY WILL BE COMPARED BETWEEN 1ST(timolol 0.5% and Brinzolamide 0.2% dual therapy ) eye drops Twice daily for 12 weeks. Control Intervention1

Eligibility

Inclusion criteria

Inclusion criteria: All patients above 40 yrs of age having all any of the features of open angle glaucoma with open angle on gonioscopy.

Exclusion criteria

Exclusion criteria: Patients other than open angle glaucoma optic neuropathies from other causes using topical or systemic corticosteroids ho hypersensitivity to any component under study patient below 40 yrs of age kco any cvs, respiratory or cns illness. pregnant or nursing women.

Design outcomes

Primary

Measure	Time frame
To compare drug efficacy of drug lowering efficacy between timolol/brinzolamide and travoprost monotherapy.Timepoint: Follow Up Schedule Baseline, 2nd, 4th, 8th, 12th week.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactLakshya

Meenakshi Medical college and research Institute of Medical Science

drindhu_ca@yahoo.co.in9003542691

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026