Health Condition 1: I493- Ventricular premature depolarization
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Case: Subject age between 18 to 80 years with documented ventricular extrasystoles and a structurally normal heart with LV EF more than 55% Control group: Subjects aged between 18 to 80 years with normal ECG and a structurally normal heart with LV EF more than 55%
Exclusion criteria
Exclusion criteria: Subjects with a history of atrial fibrillation, atrial flutter, and conduction abnormalities. Subjects with uncontrolled hypertension or with grade 2 to 3 hypertension. Subjects with diabetes using insulin. Subjects with a poor echocardiographic window.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LV strain ( GLS and torsion) RV strain ( free wall and global longitudinal strain )Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| LVEF, RV function (TAPSE, RV S ), diastolic parameters (E/A, E/e ), correlation of PVC burden with myocardial strain, and assessment of PVC site of origin (right ventricular vs left ventricular origin.Timepoint: During the same echocardiographic examination, including analysis of pre-extrasystolic , post-extrasystolic, and at extrasystolic beats | — |
Countries
India
Contacts
Manipal Collage of Health Professions , MAHE, Manipal