Comparison of two root canal cleaning solutions in children undergoing treatment for infected primary teeth

Comparative Evaluation of Antibacterial Efficacy of Sodium Hypochlorite and Sodium Hypochlorite Combined with Etidronic Acid as Irrigant in Primary Molars: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/111269

Enrollment

Registered

2026-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Sodium Hypochlorite Combined With Etidronic Acid: A combination of two point five percent sodium hypochlorite and nine percent etidronic acid prepared using Twin Kleen will be used as t

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 4 to 8 years requiring pulpectomy in primary multirooted molars. Teeth with irreversible pulpitis having adequate coronal structure to support rubber dam isolation and having at least two-thirds of root length. Patients who have not received antibiotics within the last 4 weeks prior to microbiological sampling.

Exclusion criteria

Exclusion criteria: Teeth with unrestorable crowns. Teeth with abnormal anatomy or calcified canals. Teeth with extensive internal or external root resorption or excessive mobility. Teeth requiring pulp therapy due to periodontal reasons. Patients with any systemic disease. Patients who have received antibiotics within the last 4 weeks.

Design outcomes

Primary

Measure	Time frame
Reduction in intracanal bacterial load of Enterococcus faecalis following irrigation with sodium hypochlorite and sodium hypochlorite combined with etidronic acid in primary molars undergoing pulpectomy.Timepoint: 2 years 2 months	—

Secondary

Measure	Time frame
Comparison of reduction in intracanal bacterial load between sodium hypochlorite and sodium hypochlorite combined with etidronic acid.Timepoint: 2 years 2 months	—

Countries

India

Contacts

Public ContactNishigandha Kamble

MIDSR Dental College, Latur, Maharashtra

nishigandhakamble0113@gmail.com8830656246

Outcome results