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Comparing two drugs to improve pain relief in a nerve block for postoperative facial pain in patients undergoing functional endoscopic sinus surgery

The effect of Ultrasound-guided pterygopalatine ganglion block using ropivacaine-dexamethasone or dexmedetomidine as adjuvants on postoperative pain in patients undergoing Functional endoscopic sinus surgery under general anesthesia: A randomized, double-blinded, parallel group trial. - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/111253
Enrollment
110
Registered
2026-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: Ropivacaine with dexamethasone: Patients received ultrasound-guided pterygopalatine ganglion block with 0.2% ropivacaine 5 ml plus dexamethasone 0.1 mg/kg (total volume 6 ml) after indu

Sponsors

Sir Sunderlal Hospital, IMS, BHU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-60 years 2. Patients belonging to American Society of Anaesthesiologists (ASA) physical status I and II 3. Patients posted for elective FESS 4. Patients providing written informed consent

Exclusion criteria

Exclusion criteria: 1. Known allergy to the study drugs 2. Coagulopathy or bleeding disorders 3. Infection at the site of block 4. Severe cardiovascular, hepatic, renal or neurologic disorders 5. Chronic opioid or steroid use 6. Pregnancy or lactation

Design outcomes

Primary

MeasureTime frame
To compare the duration and quality of postoperative analgesia provided by ropivacaine combined with dexamethasone versus ropivacaine combined with dexmedetomidine when used for ultrasound-guided pterygopalatine ganglion block in patients undergoing functional endoscopic sinus surgeryTimepoint: VAS score at 0, 2, 4, 6, 12, 18, 24 hours after the completion of surgery—

Secondary

MeasureTime frame
1. To compare postoperative pain scores (VAS) at predetermined time intervals between the two groups. 2. Total dose of rescue analgesic consumption within the first 24 hours. 3. Intraoperative hemodynamic stability. 4. To evaluate the adverse effects related to block or adjuvant drugs. 5. To assess patient satisfaction. Timepoint: VAS score at 0, 2, 4, 6, 12, 18, 24 hours after the completion of surgery—

Countries

India

Contacts

Public ContactDr Atul Kumar Singh

IMS BHU

atulksingh84@gmail.com08317010317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026