A study in patient undergoing awake flexible bronchoscopy to see whether nebulized dexmedetomidine with lignocaine works better than lignocaine alone in improving patient comfort

A randomized study to compare the efficacy of nebulized dexmedetomidine and lignocaine inhalation versus lignocaine inhalation alone as premedication for awake flexible fiber optic bronchoscopy at sawai man singh medical collage jaipur - Nill

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/111212

Enrollment

Registered

2026-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: patient will receive nebulization 4ml of 4% lignocaine and dexmedetomidine 1 mcg per kg total volume 6 ml: after receiving the patient in ot PAC ,consent checked vitals attached now pa

Eligibility

Inclusion criteria

Inclusion criteria: scheduled for elective surgery under general anaesthesia requiring awake fiber optic endotracheal intubation age 18 to 50 yr ASA physical status grade 1 and 2

Exclusion criteria

Exclusion criteria: history of bleeding diathesis history of loss of consciousness cervical spine instability and trauma patient obesity BMI more than 30 kg per meter square uncontrolled hypertension history of ischemic heart disease CVA stroke

Design outcomes

Primary

Measure	Time frame
To determine and compare the intubation score patient satisfaction score in both the groupTimepoint: At the time of intubation	—

Secondary

Measure	Time frame
1. to determine and compare the haemodynamic parameters HR SBP DBP MAP SPO2 in both the group. 2. to assess and compare the sedation level using Ramsay sedation score in both the group. 3. to assess and compare the proportion of side effect bradycardia bronchospasm laryngospasm if any Timepoint: 1. At prenebulization, preintubation 0 min, 2 min, 5 min, 10 min 2. prenebulization, postnebulization, preintubation, postextubation	—

Measure

Time frame

1. to determine and compare the haemodynamic parameters HR SBP DBP MAP SPO2 in both the group. 2. to assess and compare the sedation level using Ramsay sedation score in both the group. 3. to assess and compare the proportion of side effect bradycardia bronchospasm laryngospasm if any Timepoint: 1. At prenebulization, preintubation 0 min, 2 min, 5 min, 10 min 2. prenebulization, postnebulization, preintubation, postextubation

—

Countries

India

Contacts

Public ContactDr Priyanka Kanwar

sawai man singh medical collage and attached hospital

archveer.ss@gmail.com8890160492

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026