Health Condition 1: M17- Osteoarthritis of knee
Conditions
Interventions
None listed
Sponsors
Central Council for Research in Ayurvedic Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Individuals aged 50 to 65 years, previously or new, diagnosed with knee osteoarthritis (OA) using clinical and radiographic criteria of the American College of Rheumatology criteria. 2. Kellgren-Lawrence score of at least grade 2 in the knee X-ray images. 3. Written consent form. [ACR criteria for Diagnosis of Knee OA using history, physical examination and radiographic findings per Altman, R, et al.: Arthritis Rheum 34:505, 1991]
Exclusion criteria
Exclusion criteria: 1. Knee pain attributed to congenital dysplasia, rheumatoid arthritis, autoimmune diseases, malignancies, or prior knee surgeries/arthroscopy. 2. Recent administration of chondroprotective drugs, intra-articular injections into the affected knee, or systemic corticosteroids within the past three months. 3. Initiation of any new osteoarthritis (OA) treatment in the last four weeks, excluding over-the-counter analgesics like paracetamol or NSAIDs. 4. Presence of acute mental disorders, serious acute organic diseases, serious chronic comorbidities, or obesity at least at World Health Organization (WHO) grade II. 5. Blood coagulation disorders or use of coagulation-inhibiting medications (excluding acetylsalicylic acid and clopidogrel). Invasive joint procedureswithin the past 12 weeks or planned in the next 12 months. 6. Exclusion based on any severe comorbidity preventing participation in trial interventions (e.g., cardiac failure). 7. Pitta Prakriti (more than 60 percent pitta score on the Prakriti assessment scale).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in WOMAC scoreTimepoint: 0, 12th, 23nd, 30th, 45th day and 60th day | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Net Promoter Score (NPS) Scale Rating, b. Patient Satisfaction Questionnaire (PSQ-18) Score. c. Use of OTC painkillers or NSAIDS d. Visual Analog Scale for Pain e. Any adverse events.Timepoint: a. Net Promoter Score (NPS) Scale Rating - 30th day b. Patient Satisfaction Questionnaire (PSQ-18) Score - 30th day c. Use of OTC painkillers or NSAIDS - 0, 12th, 23nd, 30th, 45th day and 60th day d. Visual Analog Scale for Pain - 0, 12th, 23nd, 30th, 45th day and 60th day e. Any adverse events - 12th, 23nd, 30th, 45th day and 60th day | — |
Countries
India
Contacts
Public ContactDr Vikas Nariyal
CCRAS-RARI, Mandi
Outcome results
None listed