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Association between Risk of Diabetes and Healing after Root Canal Treatment in Patients with Tooth Root Infection

Association between diabetes risk status and endodontic treatment outcomes: a prospective observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/111133
Enrollment
110
Registered
2026-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Nil: Nil

Sponsors

Rajendra Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients having pulpal necrosis in mature mandibular molar as confirmed by negative response to pulp sensibility test (cold and electric pulp test). 2. Radiographic evidence of apical periodontitis in the form of periapical radiolucency with periapical index (PAI) scores of 3 or more.

Exclusion criteria

Exclusion criteria: 1. Patients having a positive history of antibiotic use within the past month or requiring antibiotic premedication for dental treatment (including infective endocarditis or prosthetic joint prophylaxis). 2. Teeth having previous root fillings, unrestorable teeth, fractured or perforated roots, grade 3 mobility, periodontitis and history of recent periodontal therapy within the previous 6 months. 3. Teeth with established endodontic-periodontal lesions exhibiting less than 2 mm radiopaque bone between the root apex. 4. Patients with any known systemic inflammatory conditions or chronic diseases like diabetes, cardiovascular diseases, chronic kidney disease, and atherosclerosis.

Design outcomes

Primary

MeasureTime frame
To examine and compare treatment outcome of apical periodontitis in various risk categories of type 2 diabetesTimepoint: 1 year post treatment

Secondary

MeasureTime frame
To examine the incidence & severity of apical periodontitis in various risk categories of type 2 diabetesTimepoint: Baseline;To assess the risk of type 2 diabetes as per the Indian diabetes risk score in patients with apical periodontitis.Timepoint: Baseline

Countries

India

Contacts

Public ContactDr Gaurav Kumar

Rajendra Institute of Medical Sciences, Ranchi.

dr.gaurav1410@gmail.com9671527056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026