Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Intervention arm: Preterm infants less than 32 weeks gestation will receive sodium supplementation guided by weekly spot urinary sodium measurements. Infants with urinary sodium below p
Sponsors
Dr Ujwal
Eligibility
Inclusion criteria
Inclusion criteria: Gestational age less than or equal to 32 weeks at birth. Chronological age 14 days of life at the time of enrollment. An Outborn neonate admitted within 72 hours (3 days) of life to the NICU at St. John s Medical College Hospital.
Exclusion criteria
Exclusion criteria: Major life threatening congenital anomalies. Structural genitourinary abnormality. Renal dysfunction, defined as serum creatinine more 1.0 mg/dL or an increase of more than or equal to 0.3 mg/dL between the two most recent consecutive measurements immediately prior to initiation of study procedures. Use of diuretics within 48 hours prior to initiation of study procedures. Presence of an ostomy .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in weight-for-age Z-score: Difference in weight-for-age Z-score (based on Fenton preterm growth charts) from baseline (start of supplementation) to 36 weeks postmenstrual age or discharge, whichever occurs first. Timepoint: Change in weight-for-age Z-score: Difference in weight-for-age Z-score (based on Fenton preterm growth charts) from baseline (start of supplementation) to 36 weeks postmenstrual age or discharge, whichever occurs first. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight gain velocity (g/kg/day), Average daily increase in body weight (g/kg/day) from initiation of supplementation to study completion. Timepoint: ;Variation in length-for-age and head circumference-for-age Z-scores (Fenton growth charts) between baseline and study completion.Timepoint: ;Incidence of hypernatremia (more than 150 mEq/L) Timepoint: ;Duration of NICU stay (days) :Total number of days from birth until discharge from the NICU.Timepoint: | — |
Countries
India
Contacts
Public ContactDR UJWAL
St Johns Medical College Hospital
Outcome results
None listed