A Clinical Study Comparing Two Materials (T-PRF and Collagen Membrane) Used with a Gum Surgery Technique to Treat Gum Recession

COMPARATIVE EVALUATION OF TITANIUM-PREPARED PLATELET-RICH FIBRIN VERSUS COLLAGEN MEMBRANE IN CONJUNCTION WITH CORONALLY ADVANCED FLAP FOR TREATMENT OF CAIRO RT1 GINGIVAL RECESSIONS: A RANDOMIZED SPLIT-MOUTH CONTROLLED CLINICAL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/111077

Enrollment

Registered

2026-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil Intervention7: Nil: Nil Intervention8: Titanium prepared

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients aged 18 to 50 years 2.Presence of atleast two localised Incisors Canines Premolars comparable gingival recession defects classified as Cairo RT1 4.Recession defects with Recession depth greater than or equal to 2mm Probing depth less than or equal to 3mm 5.Adequate keratinized tissue apical to the recession defect to allow coronal advancement of the flap 6.Teeth with No caries No restorations in the cervical area No cervical abrasions requiring restoration

Exclusion criteria

Exclusion criteria: 1.Patients with systemic diseases affecting wound healing eg uncontrolled diabetes immunocompromised states 2.Pregnant or lactating women 3.Smokers and tobacco users smoking or smokeless tobacco 4.Teeth with Cervical caries Restorations extending to the CEJ 5.Malpositioned teeth severe rotation or labial displacement 6.Periodontally compromised teeth 7.Recession defects classified as Cairo RT2 or RT3 8.Patients on medications affecting periodontal healing eg steroids bisphosphonates 9.Patients with poor plaque control or noncompliance

Design outcomes

Primary

Measure	Time frame
Effectiveness of Titanium prepared platelet rich fibrin vs Collagen membrane in recession defectsTimepoint: 1,3 and 6th month	—

Secondary

Measure	Time frame
Clinical Attachment Level (CAL) gain Width of Keratinized Tissue (WKT/KTW) Gingival Thickness (GT) Recession Width (RW) reductionTimepoint: 1,3 and 6th month	—

Countries

India

Contacts

Public ContactDr Harsha MB

Sri Hasanamba Dental College And Hospital

harshamb@yahoo.com9845735007

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026