Health Condition 1: S062- Diffuse traumatic brain injury
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients admitted with severe TBI Admission GCS between 3 to 8 2.Age between 18 and 70 years of either gender 3.GCS less than or equal to 12 at recruitment 4.Spontaneously breathing 5.Informed consent
Exclusion criteria
Exclusion criteria: 1.Patients requiring mechanical ventilation 2. Hemo dynamically unstable 3.Surgical site infection 4.Presence of Deep vein thrombosis 5.Mental retardation, psychiatric illness 6.Hearing loss 7. Status epilepticus 8. Dyselectrolytemia 9. Refusal to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To study the variation in cortical hemodynamic response (changes in oxyhemoglobin, deoxyhemoglobin, total hemoglobin) to tasks measured with fNIRS in patients recovering from severe TBI 2. And to correlate fNIRS findings with outcome at 30 days, 3 months, and 6 months after injury using Glasgow Outcome Scale Extended (GOS-E) Timepoint: day 7 to 14 of injury,at 30 days, 3 months, and 6 months after injury using Glasgow Outcome Scale Extended (GOS-E) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To correlate the Coma Recovery Scale Revised scores with the fNIRS findingsTimepoint: during analysis | — |
Countries
India
Contacts
Public ContactDr V J Ramesh
National Institute of Mental Health and Neurosciences
Outcome results
None listed