Comparison of Two Methods PRF and Dermal Matrix for Improving Gum Tissue Around Immediate Dental Implants A Clinical Study

Comparative Evaluation Of Periimplant Tissue Augmentation Using Leucocyte PRF And Acellular Dermal Matrix With Socket Sealing Abutment In Mandibular Posterior Immediate Implants A Randomized Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/111005

Enrollment

Registered

2026-05-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified Health Condition 2: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Leucocyte-PRF for periimplant tissue augmentation with socket sealing abutment In Mandibular Posterior Immediate Implants: After informed consent and Phase I therapy, atraumatic extr

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients aged 18 55 years 2)Systemically healthy ASA I II. 3)Indicated for extraction and immediate implant placement for split mouth case. 4)Good oral hygiene 5)Patients willing to participate and attend follow-ups.

Exclusion criteria

Exclusion criteria: Patients with uncontrolled systemic diseases or conditions that could impair healing were excluded from the study. Individuals who were current smokers (more than 10 cigarettes per day) or users of smokeless tobacco were also not included. Pregnant or lactating women were excluded, along with patients taking medications such as steroids, immunosuppressants, or bisphosphonates. Subjects presenting with active periodontal disease or peri-implantitis at the study site were not considered. Additionally, patients who had undergone recent periodontal surgery or had taken antibiotics within the past three months were excluded. Those with known allergies to acellular dermal matrix or any of the study materials were also not eligible. Patients demonstrating poor oral hygiene or lack of compliance with follow-up visits were excluded, as were individuals who had received soft-tissue grafting at the study site within the previous 12 months. Finally, patients who were unable to provide informed consent were not included in the study.

Design outcomes

Primary

Measure	Time frame
1.Change in peri-implant gingival soft-tissue thickness 2.Change in keratinized mucosal width 3.Probing depth 4.Attached mucosal width 5.Crestal bone level 6.Peri-implant bone thicknessTimepoint: Measured at baseline,after 3 months of placement and 6 months of placement	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Mangesh Phadnaik

Governmental Dental College and Hospital Nagpur

drmbphadnaik@gmail.com9422254404

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026