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Randomised controlled trial comparing efficacy and safety of basal-bolus subcutaneous insulin vs continuous IV insulin infusion in achieving target blood glucose in admitted non critical patients with T2 DM

Randomised controlled trial comparing efficacy and safety of basal-bolus subcutaneous insulin vs continuous IV insulin infusion for glycemic control in non critical patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110993
Enrollment
100
Registered
2026-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E11- Type 2 diabetes mellitus

Interventions

Intervention1: IV insulin infusion,: First group will receive basal bolus subcutaneous insulin, at ADA recommended dose of 0.3 to 0.6 units per kg with 50 percent of total daily dose given as basal an

Sponsors

Kalinga institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All inpatients with type 2 Diabetes aged more than or equal to 18years presenting with hyperglycemia

Exclusion criteria

Exclusion criteria: Patients requiring ICU admission Patients presenting with DKA or HHS Hemodynamic instability sepsis Acute coronary syndrome Gestational diabetes Patients on TPN Patients on steroid therapy Patients with EGFR less than 30 ml per min Patients with DCLD that is Child pugh B and C Type 1 Diabetes

Design outcomes

Primary

MeasureTime frame
To compare the time taken to achieve the target blood glucose 100 to 180mg per dl between basal bolus regimen and IV insulin infusion in non critical patients. Target blood glucose is said to be achieved if blood glucose fluctuations remains within target for 6 continuous hoursTimepoint: At the time of admission and hourly capillary blood glucose will be monitored until target blood glucose is achieved

Secondary

MeasureTime frame
To note incidence of hypoglycemia episodes between basal bolus regimen & IV insulin infusion in non critical patients To study the total insulin dose required to achieve target blood glucose To compare glycemic variability indices between 2 arms Timepoint: At the time of admission & hourly capillary blood glucose will be monitored till the target blood glucose is achieved

Countries

India

Contacts

Public ContactDr Arun Kumar Choudhury

Kalinga institute of medical sciences

arunchou39@gmail.com9338055566

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026