Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: 6 Week voice Rehabilitation Therapy: Non-Laryngeal Head and Neck
Cancer Patient Who received
Chemoradiation Therapy With
Voice rehabilitation for 6
weeks
Control Intervention1: No Voice
Sponsors
Indra Gandhi Medical College Shimla HP
Eligibility
Inclusion criteria
Inclusion criteria: Non-laryngeal head and neck cancer (oral cavity, oropharynx, nasopharynx, or hypopharynx) confirmed by biopsy and planned for definitive concomitant chemoradiotherapy (CRT) OR Radiotherapy alone. No prior treatment (radiotherapy, or chemotherapy) for head and neck cancer. Baseline voice grade no worse than moderate dysphonia (to allow assessment of change). Adequate hearing and cognitive function to participate in voice assessments and therapy.
Exclusion criteria
Exclusion criteria: Primary laryngeal cancer or direct involvement of the Larynx by cancer of other site. Pre-existing voice or speech disorders unrelated to cancer (e.g. neurological dysarthria, vocal cord paralysis). Prior laryngeal surgery / Recurrent nerve Palsy. Patients with advanced T3 or T4 stage head and neck malignancies. Patients with initially non-laryngeal disease that has progressed to involve the larynx. Severe comorbid conditions preventing participation (e.g. uncontrolled cardiopulmonary disease). Neurological disease affecting laryngeal muscles. Inability or unwillingness to attend follow-up visits. Chemoradiotherapy defaulter
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective: To determine the beneficial effect of voice rehabilitation on subjective voice outcomes in non-laryngeal head and neck cancer patients undergoing chemoradiotherapy.Timepoint: baseline ,Mid CRT ,completion of CRP and 3 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate changes in perceptual voice quality (using the GRBAS scale) after chemo radiation therapy (CRT) with and without voice therapy. 2. To assess changes in speech intelligibility (using a standardized Speech Intelligibility Assessment) and overall voice clarity (OVCAscore) 3. To compare the trajectory of voice recovery between patients receiving vocal rehabilitation and a control groupTimepoint: baseline ,mid CRT, completion of CRP and 3 month | — |
Countries
India
Contacts
Public ContactDr Jagdeep S Thakur
Indria Gandhi Medical College
Outcome results
None listed