Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis
Conditions
Interventions
Control Intervention1: Desflurane: Desflurane is administered via inhalation route at 3-6% concentration continuously throughout the laparoscopic cholecystectomy procedure and pupillary response is as
Sponsors
Swami Rama Himalayan university
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists physical status ASA I II Posted for elective laparoscopic cholecystectomy requiring general anaesthesia with controlled ventilation along with LMA insertion Duration of surgery less than 120 mins Subject giving consent
Exclusion criteria
Exclusion criteria: Refusal to Participate ASA Grade III and IV PatientS Patients with glaucoma, cataract, perforated eye injury, corneal injury or any other ophthalmic pathology Patients with recent URTI Patient with anticipated difficult airway Patients with significant comorbidities cardiopulmonary disease, hepatic dysfunction, renal dysfunction, endocrinologist disturbance, neurological disorder, psychiatric disorder. History of any drug allergy History of drug abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study and compare pupillary response on sevoflurane and desflurane at different time intervalTimepoint: Before Induction After LMA Insertion 45 min after induction 90 min after induction After Extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess hemodynamic correlation with pupil size and QPi Score at different stages of anaesthesiaTimepoint: Before induction After LMA insertion 45 min after induction 90 min after induction After extubation | — |
Countries
India
Contacts
Public ContactDr Divya Gupta
Himalayan institute of medical sciences
Outcome results
None listed