None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: i. Neonates with gestational age more than 30 weeks ii. Inborn neonates delivered in the study centre iii. Neonates clinically stable enough to undergo bedside ultrasonography iv. Neonates admitted either to postnatal ward or NICU
Exclusion criteria
Exclusion criteria: i. Major congenital brain malformations ii. Critical congenital heart disease (duct-dependent or cyanotic lesions) iii. Severe perinatal asphyxia requiring prolonged cardiopulmonary resuscitation iv. Major chromosomal anomalies or syndromic features v. Neonates in whom adequate Doppler window cannot be obtained vi. Severe respiratory distress requiring mechanical ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess cerebral autoregulation patterns using serial transcranial Doppler in term and preterm neonates during the first 24 hours of lifeTimepoint: To assess cerebral autoregulation patterns using serial transcranial Doppler in term and preterm neonates during the first 24 hours of life | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the temporal changes in cerebral blood flow parameters at predefined postnatal time points. To correlate cerebral doppler parameters with systemic hemodynamics or echocardiographic parameters.Timepoint: Assessments will be performed: - Within thirty minutes of life - At approximately sixty minutes of life - At approximately six hours of life - at approximately twenty four hours of life | — |
Countries
India
Contacts
KLE Academy of Higher Education and Research