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Study on the Effect of Ksheera Shatpal Ghrita in Preventing Liver Problems in Tuberculosis Patients Taking Anti-Tubercular Medicines

Clinical Evaluation of Ksheera Shatpal Ghrita As A Counter To Drug Induced Hepatotoxicity In Patients Receiving Anti Tubercular Treatment - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110899
Enrollment
28
Registered
2026-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T366- Poisoning by, adverse effect of and underdosing of rifampicins

Interventions

None listed

Sponsors

Mohd Monish
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients exhibiting symptoms of AT-DIH,after starting ATT Therapy based upon the criteria established by Indian Network For DILI 2. Patients Willing for trial. 3. Patients aged between 20 years to 70 years of age.

Exclusion criteria

Exclusion criteria: 1. Patients having history of other diseases or taking medications which can alter the interpretation of Liver Function Tests. 2. Patients who are chronic alcoholics or have history of any other substance abuse. 3. Patients taking other Hepatoprotective or Hepatotoxic drugs. 4. Patients having secondary dyslipidemia 5. Patients having low levels of Albumin prior to starting ATT Treatment.

Design outcomes

Primary

MeasureTime frame
Relief in Subjective Parameters 1. Utklesha (Nausea) 2. Chardi ( Vomiting) 3. Aruchi (Loss of Appetite) 4. Hridkanthdah (Epigastric Discomfort) 5. Udarshoola (Abdominal Pain)Timepoint: Outcome will be assessed at baseline,1st week,2nd week,3rd week and after completion of treatment at 4th week. Follow up will be done at an interval of 30 days after the commencement of trial ( 2 follow ups in 2 months)

Secondary

MeasureTime frame
Relief in Objective Parameters 1. LFT 2. Lipid ProfileTimepoint: Outcome will be assessed at baseline,1st week,2nd week,3rd week & after completion of treatment at 4th week. Follow up will be done at an interval of 30 days after the commencement of trial ( 2 follow ups in 2 months)

Countries

India

Contacts

Public ContactMohd Monish

Quadra Institute of Ayurveda and Hospital Roorkee

drrajnikant83@gmail.com8054114530

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026