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STUDY THE EFFECT OF PROPOFOL ON ARTERIAL BLOOD PRESSURE AND CEREBRAL ARTERY BLOOD FLOW VELOCITY IN INFANTS UPTO 1 YEARS UNDERGOING VENTRICULOPERITONEAL SHUNT SURGERY USING TRANSCRANIAL DOPPLER WHICH IS NON INVASIVE AND EDUCATIVE

STUDY OF THE EFFECT OF PROPOFOL ANAESTHESIA ON CEREBRAL HAEMODYNAMIC IN INFANTS UNDERGOING VENTRICULOPERITONEAL SHUNT SURGERY A PROSPECTIVE OBSERVATIONAL STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/110880
Enrollment
64
Registered
2026-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G911- Obstructive hydrocephalus

Interventions

Intervention1: Nil: Nil

Sponsors

DR RAM MANOHAR LOHIYA HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consent from patients guardian Infants undergoing ventriculoperitoneal shunt surgery

Exclusion criteria

Exclusion criteria: Failure to get consent from patients guardian Previous history of Ventriculoperitoneal shunt insertion or any other surgery Any symptom or sign of Meningitis Failure to extubate within 30 minutes after surgery completion

Design outcomes

Primary

MeasureTime frame
Propofol is expected to decrease mean arterial blood pressure more than the decrease in anterior cerebral artery blood flow velocity, suggesting that brain is autoregulating Timepoint: 1Baseline TCD (Transcranial Doppler) Reading 2After oxygenation 3After induction 41 minute after intubation 55 minute after intubation 6After shunt insertion 7TCD reading every 5 minutes thereafter 8Before extubation TCD reading 9 After extubation TCD reading—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactPARUL UPADHYAY

DR RAM MANOHAR LOHIYA INSTITUTE MEDICAL SCIENCES

samikshaparashar@gmail.com7042345280

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026