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Dual fascial plane block- enabled fast track recovery: A randomized comparison of two drugs (Dexmedetomidine and Dexamethasone) as adjuvants to regional anesthesia (Transversus thoracic muscle plane and serratus anterior plane blocks) in adult cardiac surgery via median sternotomy.

Dual fascial plane block enabled fast track recovery: A randomized comparison of Dexmedetomidine and Dexamethasone as adjuvant to Transversus Thoracic Muscle plane and Serratus Anterior Plane block in adult cardiac surgery via median sternotomy - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110838
Enrollment
60
Registered
2026-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I252- Old myocardial infarction

Interventions

Intervention1: To compare the efficacy of Dexmedetomidine as adjuvants to ultrasound-guided dual fascial plane blocks (Transversus Thoracic Muscle Plane Block combined with Serratus Anterior Plane blo

Sponsors

Postgraduate Institute of Medical Education and Research Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients undergoing cardiac surgery via midline sternotomy. 2.Patients under American society of anesthesiologist class I to III

Exclusion criteria

Exclusion criteria: Patients with contraindication to Transversus Thoracic Muscle Plane Block or Serratus Anterior Plane block Patients with history of allergies to local anesthetics. Local site infection Severe pulmonary artery hypertension Redo cardiac surgery. Severe PAH. Poor Ejection Fraction Emergency surgery Anticipated patients requiring mechanical ventilation for more than 24 hours postoperatively.

Design outcomes

Primary

MeasureTime frame
To compare cumulative opioid (fentanyl) consumption within the first 24 hours between patients receiving Dexmedetomidine and those receiving Dexamethasone as adjuvants to dual fascial plane blocks following median sternotomy.Timepoint: 24 HOURS—

Secondary

MeasureTime frame
1. To evaluate and compare the time to extubation between the study groups 2. To compare intraoperative fentanyl requirement. 3. To compare postoperative fentanyl consumption between both groups. 4. To compare postoperative pain scores at rest and during coughing using the Numerical Rating Scale (NRS) at 6, 12, and 24 hours. 5. To compare the time to first requirement of rescue analgesia. 6. To analyze and compare the incidence of adverse events, including: Hypotension Bradycardia Respiratory depression Postoperative nausea and vomiting (PONV) Timepoint: 24 HOURS—

Countries

India

Contacts

Public ContactKulbhushan Saini

Cardiac Anesthesia and Intensive Care

kulbhushansaini007@gmail.com9968856948

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026